Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242979 | 0.95 | HTT (0.42) | HTTSCN4ACYP3A4USP2SPHK1 | |
| SCHEMBL11242156 | 0.89 | SCN4A (0.39) | HTTSCN4ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL12212746 | 0.88 | HTT (0.52) | HTTSCN4ACYP3A4USP2SPHK1 | |
| SCHEMBL635567 | 0.86 | CYP3A4 (0.44) | HTTSCN4ACYP3A4 | |
| SCHEMBL26049246 | 0.84 | — | — | |
| SCHEMBL9629070 | 0.83 | HTT (0.35) | HTTSCN4ACYP3A4SPHK1ALDH1A1 | |
| SCHEMBL12190568 | 0.80 | HTT (0.33) | HTT | |
| SCHEMBL11535497 | 0.78 | SCN4A (0.33) | HTTSCN4A | |
| SCHEMBL16826803 | 0.78 | CA2 (0.34) | HTTSCN4A | |
| SCHEMBL12972157 | 0.78 | HTT (0.33) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328331-A | Novel polyester-amides | THE UPJOHN COMPANY (US) | 1982-05-04 | — | — | US | disclosed |