Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540945 | 0.75 | GRIA1 (0.56) | GRIA1GRIA2GRIA4GRIK5PDE3A | |
| SCHEMBL12294592 | 0.75 | GRIA1 (0.51) | GRIA1GRIA2GRIA4GRIK5PDE3A | |
| SCHEMBL11402130 | 0.72 | GRIA1 (0.49) | GRIA1GRIA2GRIA4GRIK5ADORA2B | |
| SCHEMBL11234127 | 0.70 | GRIA1 (0.47) | GRIA1GRIA2GRIA4GRIK5ADORA2B | |
| SCHEMBL22119620 | 0.69 | GDA (0.33) | ADORA2BADORA3CYP3A4LMNAALDH1A1 | |
| SCHEMBL2723681 | 0.69 | PDE3A (0.51) | GRIA1GRIA2GRIA4GRIK5ADORA2B | |
| SCHEMBL6268666 | 0.68 | PDE3A (0.47) | GRIA1GRIA2GRIA4GRIK5PDE3A | |
| SCHEMBL11302701 | 0.68 | GRIA1 (0.45) | GRIA1GRIA2GRIA4GRIK5PDE3A | |
| SCHEMBL30861196 | 0.67 | CYP3A4 (0.48) | ADORA2BADORA3CYP3A4ADORA2ALMNA | |
| SCHEMBL22119225 | 0.66 | EGLN1 (0.36) | LMNAALDH1A1PKMRECQLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583919-B | Preparation method of 6-oxyalkyl 1,2, 4-triazine-3, 5 (2H, 4H) -diketone derivative | 河北工业大学 | 2024-04-19 | — | — | CN | claimed |
| CN-115583919-A | Preparation method of 6-oxyalkyl 1,2,4-triazine-3,5 (2H, 4H) -diketone derivative | 河北工业大学 | 2023-01-10 | — | — | CN | claimed |
| JP-56152468-A | — | — | None | — | — | JP | disclosed |
| CN-115583919-B | Preparation method of 6-oxyalkyl 1,2, 4-triazine-3, 5 (2H, 4H) -diketone derivative | 河北工业大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-115583919-A | Preparation method of 6-oxyalkyl 1,2,4-triazine-3,5 (2H, 4H) -diketone derivative | 河北工业大学 | 2023-01-10 | — | — | CN | disclosed |
| US-4327094-A | Insecticidal and acaricidal 3,5-dioxo-2,3,4,5-triazine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-04-27 | — | — | US | disclosed |
| JP-S56152468-A | 3,5-DIOXO-2,3,4,5-TETRAHYDRO-1,2,4-TRIAZINE DERIVATIVE AND ITS PRODUCTION | SUMITOMO CHEM CO LTD | 1981-11-26 | — | — | JP | disclosed |
| EP-0033163-A2 | 3,5-Dioxo-2,3,4,5-tetrahydro-1,2,4-triazine compounds, composition containing them, their use as insecticides and acaricides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-08-05 | — | — | EP | disclosed |