Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.56 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.56 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11402130 | 0.76 | GRIA1 (0.49) | GRIA1GRIA2GRIA4GRIK5PDE3A | |
| SCHEMBL11241808 | 0.75 | GRIA1 (0.47) | GRIA1GRIA2GRIA4GRIK5PDE3A | |
| SCHEMBL11234127 | 0.75 | GRIA1 (0.47) | GRIA1GRIA2GRIA4GRIK5PDE3A | |
| SCHEMBL11304991 | 0.73 | GRIA1 (0.54) | GRIA1GRIA2GRIA4GRIK5PDE3A | |
| SCHEMBL2723681 | 0.73 | PDE3A (0.51) | GRIA1GRIA2GRIA4GRIK5PDE3A | |
| SCHEMBL9393484 | 0.72 | GRIA1 (1.00) | GRIA1GRIA2GRIA4GRIK5HIF1A | |
| SCHEMBL9396137 | 0.72 | GRIA1 (1.00) | GRIA1GRIA2GRIA4GRIK5HIF1A | |
| SCHEMBL9393490 | 0.72 | GRIA1 (1.00) | GRIA1GRIA2GRIA4GRIK5HIF1A | |
| SCHEMBL6268666 | 0.72 | PDE3A (0.47) | GRIA1GRIA2GRIA4GRIK5PDE3A | |
| SCHEMBL14544299 | 0.71 | GRIA1 (0.48) | GRIA1GRIA2GRIA4GRIK5PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014635-A1 | PRACTICAL METHOD FOR DETERMINING A CHEMICAL HYBRIDIZING AGENT-APPLICATION TIME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-08-05 | — | — | WO | claimed |
| US-4297129-A | HERBICIDES; WILD OATS; NONPHYTOTOXIC | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-27 | — | — | US | claimed |
| JP-55143904-A | — | — | None | — | — | JP | disclosed |
| JP-55143904-A | — | — | None | — | — | JP | disclosed |
| US-20230089582-A1 | 1,2,4-TRIAZINE-3,5-DIONE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | KPC PHARMACEUTICALS INC (CN) | 2023-03-23 | — | — | US | disclosed |
| EP-4083024-A1 | 1,2,4-TRIAZINE-3,5-DIONE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | KPC Pharmaceuticals, Inc. (CN) | 2022-11-02 | — | — | EP | disclosed |
| WO-1993014635-A1 | PRACTICAL METHOD FOR DETERMINING A CHEMICAL HYBRIDIZING AGENT-APPLICATION TIME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-08-05 | — | — | WO | disclosed |
| US-4297129-A | HERBICIDES; WILD OATS; NONPHYTOTOXIC | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-27 | — | — | US | disclosed |
| JP-S55143904-A | HERBICIDE COMPRISING 2-HYDROXYMETHYL-1,2,4-TRIAZINE-3,5-DIONE OR ITS SALT AS ACTIVE CONSTITUENT | SUMITOMO CHEM CO LTD | 1980-11-10 | — | — | JP | disclosed |
| JP-S55143904-A | HERBICIDE COMPRISING 2-HYDROXYMETHYL-1,2,4-TRIAZINE-3,5-DIONE OR ITS SALT AS ACTIVE CONSTITUENT | SUMITOMO CHEM CO LTD | 1980-11-10 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230089582-A1 | 1,2,4-TRIAZINE-3,5-DIONE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | THRB, THRA, TSHR | GRIA1 656/4885GRIA2 967/4885GRIA4 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.