SCHEMBL11241826

SCHEMBL11241826

CCCCCCCCCCCC1OCCC(CCC)S1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.52
ALDH1A1 P00352 2/20 0.41
CYP1A2 P05177 3/20 0.37
SPHK1 Q9NYA1 7/20 0.36
SPHK2 Q9NRA0 6/20 0.36
ALOX5 P09917 2/20 0.35
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11255010 1.00 EPHX1 (0.52) EPHX1ALDH1A1CYP1A2SPHK1SPHK2
SCHEMBL1308539 0.98 EPHX1 (0.48) EPHX1ALDH1A1CYP1A2SPHK1SPHK2
SCHEMBL18339141 0.98 EPHX1 (0.48) EPHX1ALDH1A1CYP1A2SPHK1SPHK2
SCHEMBL18339140 0.98 EPHX1 (0.48) EPHX1ALDH1A1CYP1A2SPHK1SPHK2
SCHEMBL11251244 0.95 EPHX1 (0.53) EPHX1ALDH1A1CYP1A2SPHK1SPHK2
SCHEMBL11245616 0.86 EPHX1 (0.52) EPHX1ALDH1A1CYP1A2SPHK1SPHK2
SCHEMBL11251253 0.82 EPHX1 (0.35) EPHX1
SCHEMBL28238221 0.80 ALDH1A1 (0.45) EPHX1ALDH1A1CYP1A2SPHK1SPHK2
SCHEMBL28581095 0.80 ALDH1A1 (0.45) EPHX1ALDH1A1CYP1A2SPHK1SPHK2
SCHEMBL1306960 0.78 EPHX1 (0.31) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4364400-A 1,3-OXATHIANE AND 1,3-OXATHIOLANE DERIVATIVES FIRMENICH SA (CH) 1982-12-21 US disclosed
US-4262030-A 1,3-OXATHIANE AND 1,3-OXATHIOLANE DERIVATIVES FIRMENICH SA (CH) 1981-04-14 US disclosed
US-4220561-A Oxathiane and oxathiolane derivatives as perfuming agents FIRMENICH SA (CH) 1980-09-02 US disclosed