Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14117962 | 0.86 | RAB9A (0.59) | KDM4EMAPTNOTUMRAB9ANPC1 | |
| SCHEMBL28717641 | 0.83 | RAB9A (0.56) | KDM4EMAPTNOTUMRAB9ANPC1 | |
| SCHEMBL5904824 | 0.83 | RAB9A (0.63) | KDM4EMAPTRAB9ANPC1KMT2A | |
| SCHEMBL11254206 | 0.81 | KDM4E (0.61) | KDM4EMAPTRAB9ANPC1KMT2A | |
| SCHEMBL720561 | 0.81 | NOTUM (0.54) | KDM4EMAPTNOTUMRAB9ANPC1 | |
| SCHEMBL11261173 | 0.80 | MAPT (0.42) | KDM4EMAPTNOTUMRAB9ANPC1 | |
| SCHEMBL5001181 | 0.80 | NOTUM (0.52) | KDM4EMAPTNOTUMRAB9ANPC1 | |
| SCHEMBL10508841 | 0.79 | KDM4E (0.71) | KDM4EMAPTRAB9ANPC1KMT2A | |
| SCHEMBL16202073 | 0.77 | CNR1 (0.47) | KDM4EMAPTNOTUMRAB9ANPC1 | |
| SCHEMBL16202074 | 0.77 | CNR1 (0.47) | KDM4EMAPTNOTUMRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |