Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.62 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.62 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.53 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30331615 | 0.98 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL157802 | 0.98 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL317924 | 0.98 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL474980 | 0.98 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL4998837 | 0.98 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL24451237 | 0.98 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL157803 | 0.98 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL10343473 | 0.98 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL4998832 | 0.98 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| Hydrochloric Acid SCHEMBL1591866 | 0.97 | CDK5 (0.62) | CDK5CDK5R1NR1I3CYP19A1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360663-A | Steroid hormone-antitumor derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4260736-A | NAPHTHACENE HEXAPYRANOSIDE DERIVATIVE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1981-04-07 | — | — | US | disclosed |