Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.64 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.64 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.54 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4998837 | 1.00 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL157802 | 1.00 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL30331615 | 1.00 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL474980 | 1.00 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL157803 | 1.00 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL24451237 | 1.00 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL4998832 | 1.00 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL10343473 | 1.00 | CDK5 (0.64) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| SCHEMBL11241858 | 0.98 | CDK5 (0.62) | CDK5CDK5R1NR1I3CYP19A1GRIN1 | |
| Hydrochloric Acid SCHEMBL1591866 | 0.98 | CDK5 (0.62) | CDK5CDK5R1NR1I3CYP19A1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1724554-A | 1,4-pregnandiene 17 alpha, 21'-dihydroxy-3,20-diketone-17 alpha, 21-diacetate | UNIV SICHUAN (CN) | 2006-01-25 | — | — | CN | claimed |
| EP-1379542-A2 | TREATMENT OF TUMOURS | Hagström, Tomas (SE) | 2004-01-14 | — | — | EP | claimed |
| WO-2002072003-A2 | USE OF STEROID DERIVATIVES FOR THE TREATMENT OF A BENIGHN AND/OR MALIGNANT TUMOUR | HAGSTROEM TOMAS (SE) | 2002-09-19 | — | — | WO | claimed |
| CN-117281815-A | Asymmetric synthesis and use of compounds in the treatment of disease | 浙江嘉驰医药开发有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-117281816-A | Asymmetric synthesis and use of compounds in the treatment of disease | 浙江嘉驰医药开发有限公司 | 2023-12-26 | — | — | CN | disclosed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| CN-111050771-B | Asymmetric synthesis and use of compounds in the treatment of disease | 浙江嘉驰医药开发有限公司 | 2023-08-01 | — | — | CN | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| CN-109503691-A | A kind of synthetic method of 5 α-androstane -3,17- diketone | 华中药业股份有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-107619424-A | A kind of preparation method of 17 hydroxyl nitrile steroid derivative | 天津金耀集团有限公司 | 2018-01-23 | — | — | CN | disclosed |
| US-9868757-B2 | 5-β, 14-β-androstane derivatives useful for the treatment of proteinuria, glomerulosclerosis and renal failure | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2018-01-16 | — | — | US | disclosed |
| CN-1100101-A | 14alpha-hydroxy-4-androstene-3,6,17-trione hydrate crystal and process for producing same | NIPPON KAYAKU KK (JP) | 1995-03-15 | — | — | CN | disclosed |
| CN-1026236-C | Steroid 5-alpha-reductase inhibitors | SMITHKLINE BECKMAN CORP (US) | 1994-10-19 | — | — | CN | disclosed |
| EP-0583606-A2 | New hydrazono-5-beta-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1994-02-23 | — | — | EP | disclosed |
| CN-1079747-A | The preparation of pharmaceutical compositions method that contains steroid 5-alpha-reductase inhibitors | SMITHKLINE BECKAMAN CORP (US) | 1993-12-22 | — | — | CN | disclosed |
| CN-1071418-A | Benzo [ f ] quinolinones | LILLY CO ELI (US) | 1993-04-28 | — | — | CN | disclosed |
| EP-0253415-B1 | PROCESS FOR THE PREPARATION OF 9(11)-DEHYDROANDROSTANES | GIST-BROCADES N.V. (NL) | 1990-03-14 | — | — | EP | disclosed |
| CN-1030765-A | STEROID 5-ALPHA-REDUCTASE INHIBITORS | SMITHKLINE BECKMAN CORP (US) | 1989-02-01 | — | — | CN | disclosed |
| EP-0253415-A1 | Process for the preparation of 9(11)-dehydroandrostanes | GIST-BROCADES N.V. (NL) | 1988-01-20 | — | — | EP | disclosed |
| US-4075233-A | SKIN DISORDERS | GIST-BROCADES N.V. (NL) | 1978-02-21 | — | — | US | disclosed |