Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Fumarate SCHEMBL11242272 | 1.00 | HCAR2 (0.48) | HCAR2ATMMAPTNPSR1RAB9A | |
| Butyl Fumarate SCHEMBL11121036 | 0.88 | ATM (0.67) | HCAR2ATMMAPTNPSR1RAB9A | |
| SCHEMBL7629302 | 0.85 | HCAR2 (0.61) | HCAR2ATMMAPTNPSR1RAB9A | |
| Fumaric Acid SCHEMBL2940732 | 0.85 | CA1 (0.41) | ATMCA1 | |
| Fumaric Acid SCHEMBL2940726 | 0.85 | CA1 (0.41) | ATMCA1 | |
| Ethyl Fumarate SCHEMBL1904369 | 0.83 | HCAR2 (0.61) | HCAR2ATMMAPTNPSR1ALDH1A1 | |
| Ethyl Fumarate SCHEMBL1904374 | 0.83 | HCAR2 (0.61) | HCAR2ATMMAPTNPSR1ALDH1A1 | |
| Ethyl Fumarate SCHEMBL20594713 | 0.83 | HCAR2 (0.61) | HCAR2ATMMAPTNPSR1ALDH1A1 | |
| Ethyl Fumarate SCHEMBL1905731 | 0.83 | HCAR2 (0.61) | HCAR2ATMMAPTNPSR1ALDH1A1 | |
| Ethyl Fumarate SCHEMBL1903287 | 0.83 | HCAR2 (0.61) | HCAR2ATMMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322519-A | USING AN ORGANOTIN COMPOUND CATALYST | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1982-03-30 | — | — | US | claimed |
| US-4322519-A | USING AN ORGANOTIN COMPOUND CATALYST | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1982-03-30 | — | — | US | disclosed |