Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239428 | 0.96 | KDM4E (0.52) | KDM4ELMNAALDH1A1QPCTKMT2A | |
| SCHEMBL11233797 | 0.89 | KDM4E (0.49) | KDM4ELMNAALDH1A1QPCTKMT2A | |
| SCHEMBL11236581 | 0.88 | KDM4E (0.48) | KDM4ELMNAALDH1A1QPCTKMT2A | |
| SCHEMBL11231921 | 0.88 | KDM4E (0.48) | KDM4ELMNAALDH1A1QPCTKMT2A | |
| SCHEMBL11247617 | 0.87 | MEN1 (0.48) | LMNAQPCTKMT2AMEN1ATM | |
| SCHEMBL11241349 | 0.84 | HMOX1 (0.52) | KDM4ELMNAALDH1A1QPCTKMT2A | |
| SCHEMBL11243106 | 0.83 | CYP19A1 (0.49) | ALDH1A1QPCTCYP19A1POLB | |
| SCHEMBL11243335 | 0.83 | HMOX1 (0.61) | — | |
| SCHEMBL11244363 | 0.83 | MEN1 (0.52) | LMNAALDH1A1QPCTKMT2AMEN1 | |
| SCHEMBL11246746 | 0.82 | MEN1 (0.50) | LMNAKMT2AMEN1ATMCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |