SCHEMBL11242487

SCHEMBL11242487

CCc1nccn1C(=NO)C(C(=O)NC)C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
KMT2A Q03164 2/20 0.31
F2 P00734 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
ALPG P10696 2/20 0.30
PLAA Q9Y263 1/20 0.30
MAPT P10636 1/20 0.30
ALPL P05186 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11238683 0.76 ALDH1A1 (0.34) ALDH1A1KMT2A
SCHEMBL11235925 0.72
SCHEMBL11233303 0.71 CYP26A1 (0.34)
SCHEMBL28746087 0.70 ALPG (0.41) KDM4EALDH1A1KMT2AF2LMNA
SCHEMBL11225659 0.69
SCHEMBL11234969 0.69 ALDH1A1 (0.36) KDM4EALDH1A1MAPT
SCHEMBL11240989 0.68 ELANE (0.38) F2
SCHEMBL11248332 0.68 KMT2A (0.32) KMT2A
SCHEMBL1165647 0.68 ALPG (0.42) KDM4EALDH1A1KMT2AF2LMNA
SCHEMBL2288576 0.68 ALPG (0.42) KDM4EALDH1A1KMT2AF2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359469-A Combating pests with N-sulphenylated oxime-carbamates BAYER AKTIENGESELLSCHAFT (DE) 1982-11-16 US disclosed