Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138733 | 0.86 | PTGS1 (0.35) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL26914662 | 0.81 | APP (0.38) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL11237895 | 0.79 | APP (0.37) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL11234467 | 0.78 | APP (0.35) | APPPTGS1PDE4A | |
| SCHEMBL25454715 | 0.76 | APP (0.34) | APP | |
| SCHEMBL25455730 | 0.75 | PTGS1 (0.30) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL11141037 | 0.73 | ALDH1A1 (0.41) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL24668890 | 0.72 | APP (0.31) | APP | |
| SCHEMBL11137356 | 0.72 | — | — | |
| SCHEMBL24137990 | 0.71 | ALDH1A1 (0.31) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328143-A | Aqueous coating composition | NIPPON PAINT COMPANY, LTD. (JP) | 1982-05-04 | — | — | US | disclosed |
| US-4322324-A | Ampho-ionic group-containing alkyd resins | NIPPON PAINT CO., LTD. (JP) | 1982-03-30 | — | — | US | disclosed |