Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.81 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.81 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30674793 | 0.92 | CYP19A1 (0.85) | MAOBCYP19A1CYP3A4NPC1MAPT | |
| SCHEMBL7655727 | 0.92 | CYP19A1 (0.85) | MAOBCYP19A1CYP3A4NPC1MAPT | |
| SCHEMBL11242828 | 0.90 | AR (0.70) | MAOBCYP19A1CYP3A4NPC1MAPT | |
| Liquiritigenin Dimethyl Ether SCHEMBL3303937 | 0.89 | CYP19A1 (1.00) | MAOBCYP19A1CYP3A4NPC1MAPT | |
| Liquiritigenin Dimethyl Ether SCHEMBL13394438 | 0.89 | CYP19A1 (1.00) | MAOBCYP19A1CYP3A4NPC1MAPT | |
| SCHEMBL10536106 | 0.88 | MAOB (0.64) | MAOBCYP19A1CYP3A4 | |
| SCHEMBL31060428 | 0.85 | MAOB (1.00) | MAOBCYP19A1CYP3A4NPC1MAPT | |
| SCHEMBL7195893 | 0.85 | CYP19A1 (0.86) | MAOBCYP19A1CYP3A4NPC1MAPT | |
| SCHEMBL31028354 | 0.85 | CYP19A1 (0.86) | MAOBCYP19A1CYP3A4NPC1MAPT | |
| SCHEMBL6700953 | 0.84 | MAOB (0.69) | MAOBCYP19A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004579-B1 | FLAVANS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-08-18 | — | — | EP | claimed |