Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 9/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242835 | 0.90 | MAOB (0.81) | ARABCB1ABCG2MAOBCYP19A1 | |
| SCHEMBL22680315 | 0.89 | ABCB1 (0.87) | ARABCB1ABCG2MAOBCYP19A1 | |
| SCHEMBL10536102 | 0.88 | AR (0.63) | ARABCB1ABCG2MAOBCYP19A1 | |
| SCHEMBL30674793 | 0.85 | CYP19A1 (0.85) | ARABCB1ABCG2MAOBCYP19A1 | |
| SCHEMBL7655727 | 0.85 | CYP19A1 (0.85) | ARABCB1ABCG2MAOBCYP19A1 | |
| SCHEMBL4951516 | 0.85 | CYP19A1 (0.73) | ARABCB1ABCG2MAOBCYP19A1 | |
| SCHEMBL6700946 | 0.84 | AR (0.69) | ARABCB1ABCG2MAOBCYP19A1 | |
| SCHEMBL126192 | 0.83 | AR (1.00) | ARABCB1ABCG2MAOBCYP19A1 | |
| SCHEMBL4394832 | 0.83 | AR (1.00) | ARABCB1ABCG2MAOBCYP19A1 | |
| SCHEMBL18893710 | 0.82 | MAOB (0.81) | ARABCB1ABCG2MAOBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004579-B1 | FLAVANS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-08-18 | — | — | EP | claimed |