Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829613 | 0.92 | DPP4 (0.57) | DPP4KMT2AMEN1MAPTPOLB | |
| SCHEMBL11240081 | 0.86 | DPP4 (0.53) | DPP4KMT2AMEN1MAPTKDM4E | |
| SCHEMBL5666906 | 0.83 | DPP4 (0.53) | DPP4KMT2AMEN1MAPTPOLB | |
| SCHEMBL13313455 | 0.81 | MEN1 (0.55) | DPP4KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11250968 | 0.81 | DPP4 (0.58) | DPP4KMT2AMEN1MAPTKDM4E | |
| SCHEMBL440489 | 0.81 | DPP4 (0.53) | DPP4KMT2AMEN1MAPTPOLB | |
| SCHEMBL18285392 | 0.80 | MEN1 (0.63) | DPP4KMT2AMEN1MAPTPOLB | |
| SCHEMBL774503 | 0.80 | MEN1 (0.67) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL18987613 | 0.79 | MEN1 (0.62) | DPP4KMT2AMEN1MAPTPOLB | |
| SCHEMBL18988084 | 0.78 | MEN1 (0.61) | DPP4KMT2AMEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343804-A | 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds | A. H. ROBINS COMPANY, INC. (US) | 1982-08-10 | — | — | US | disclosed |