Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438246 | 0.91 | DPP4 (0.56) | DPP4KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL437796 | 0.89 | NPC1 (0.54) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL440196 | 0.86 | NPC1 (0.52) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL435825 | 0.84 | HAVCR2 (0.50) | KMT2AMAPT | |
| SCHEMBL9829613 | 0.83 | DPP4 (0.57) | DPP4KMT2AMEN1POLBMAPT | |
| SCHEMBL11242887 | 0.81 | DPP4 (0.52) | DPP4KMT2AMEN1POLBMAPT | |
| SCHEMBL11250968 | 0.79 | DPP4 (0.58) | DPP4KMT2AMEN1MAPT | |
| SCHEMBL436627 | 0.78 | KMT2A (0.67) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL436903 | 0.77 | KMT2A (0.65) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL437101 | 0.77 | KMT2A (0.65) | KMT2ANPC1RAB9AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |