Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243251 | 1.00 | ACE (0.37) | ACECPB2SIGMAR1F2F10 | |
| SCHEMBL11264758 | 0.87 | GSR (0.31) | — | |
| SCHEMBL649164 | 0.82 | DPP8 (0.43) | ACECPB2 | |
| SCHEMBL5552493 | 0.82 | DPP8 (0.43) | ACECPB2 | |
| Water SCHEMBL3369508 | 0.82 | DPP7 (0.42) | ACECPB2 | |
| SCHEMBL10883512 | 0.81 | DPP7 (0.39) | ACESIGMAR1 | |
| SCHEMBL9394613 | 0.79 | ACE (0.40) | ACE | |
| Methanesulfonamide SCHEMBL11097510 | 0.78 | DPP8 (0.39) | ACECPB2 | |
| SCHEMBL7266941 | 0.72 | ACE (0.42) | ACE | |
| SCHEMBL5551908 | 0.71 | DPP8 (0.40) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058918-A1 | Aza analogs of aminoacid derivatives as antihypertensives | MERCK & CO. INC. (US) | 1982-09-01 | — | — | EP | claimed |
| EP-0058918-A1 | Aza analogs of aminoacid derivatives as antihypertensives | MERCK & CO. INC. (US) | 1982-09-01 | — | — | EP | disclosed |