Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | PLAUR | Q03405 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552493 | 1.00 | DPP8 (0.43) | DPP8DPP7DPP9ACEMMP2 | |
| Water SCHEMBL3369508 | 0.99 | DPP7 (0.42) | DPP8DPP7DPP9ACEMMP2 | |
| SCHEMBL10883512 | 0.97 | DPP7 (0.39) | DPP8DPP7DPP9ACEMMP2 | |
| Methanesulfonamide SCHEMBL11097510 | 0.94 | DPP8 (0.39) | DPP8DPP7DPP9ACEMMP2 | |
| SCHEMBL7266941 | 0.89 | ACE (0.42) | DPP8DPP7DPP9ACEOPRK1 | |
| SCHEMBL5551908 | 0.87 | DPP8 (0.40) | DPP8DPP7DPP9ACEMMP2 | |
| SCHEMBL7318606 | 0.86 | DPP7 (0.43) | DPP8DPP7DPP9DPP4FAP | |
| SCHEMBL10887856 | 0.85 | DPP7 (0.37) | DPP8DPP7DPP9DPP4 | |
| SCHEMBL9394613 | 0.84 | ACE (0.40) | ACEDPP4 | |
| SCHEMBL11242902 | 0.82 | ACE (0.37) | ACECPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119817-B2 | Process for separating the diastereomers of RSS-and SSS-N- α [1-carboxy-3-phenylpropyl] lysylproline | DEGUSSA-HUELS AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20110077412-A1 | Process for separating the diastereomers of RSS-snd SSS-N- a [1-carboxy -3-Phenylpropyl] lysylproline | DEGUSSA-HUELS AG (DE) | 2011-03-31 | — | — | US | disclosed |