Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.80 |
| ▸ | AR | P10275 | 9/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.80 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22171576 | 0.90 | PGR (0.83) | PGRARHIF1ACYP3A4ADORA3 | |
| Clocortolone Pivalate SCHEMBL10052573 | 0.89 | PGR (1.00) | PGRARHIF1ACYP3A4ADORA3 | |
| Diflucortolone Pivalate SCHEMBL668257 | 0.89 | PGR (0.81) | PGRARHIF1ACYP3A4ADORA3 | |
| Clocortolone Pivalate SCHEMBL32668843 | 0.89 | PGR (1.00) | PGRARHIF1ACYP3A4ADORA3 | |
| Clocortolone Pivalate SCHEMBL5120 | 0.89 | PGR (1.00) | PGRARHIF1ACYP3A4ADORA3 | |
| Clocortolone Pivalate SCHEMBL6834795 | 0.89 | PGR (1.00) | PGRARHIF1ACYP3A4ADORA3 | |
| Clocortolone Pivalate SCHEMBL13423591 | 0.89 | PGR (1.00) | PGRARHIF1ACYP3A4ADORA3 | |
| Diflucortolone Pivalate SCHEMBL668256 | 0.89 | PGR (0.81) | PGRARHIF1ACYP3A4ADORA3 | |
| SCHEMBL11684094 | 0.86 | PGR (0.61) | PGRARHIF1ACYP3A4ADORA3 | |
| SCHEMBL11684088 | 0.86 | PGR (0.61) | PGRARHIF1ACYP3A4ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315866-A | Process for preparing 11-keto steroids | SCHERING, A.G. (DE) | 1982-02-16 | — | — | US | disclosed |
| EP-0030368-A1 | Process for the preparation of 11-keto steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-06-17 | — | — | EP | disclosed |