Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243041 | 1.00 | NPY1R (0.40) | NPY1RNPY2RNPY4RNPY5RHRH1 | |
| SCHEMBL11243039 | 1.00 | NPY1R (0.40) | NPY1RNPY2RNPY4RNPY5RHRH1 | |
| SCHEMBL11236266 | 0.85 | HTR2B (0.42) | NPY1RNPY2RNPY4RNPY5RSLC6A2 | |
| SCHEMBL11244532 | 0.85 | HTR2B (0.42) | NPY1RNPY2RNPY4RNPY5RSLC6A2 | |
| SCHEMBL11230983 | 0.85 | TDP1 (0.50) | NPY1RNPY2RNPY4RNPY5RTDP1 | |
| SCHEMBL11236271 | 0.85 | HTR2B (0.42) | NPY1RNPY2RNPY4RNPY5RSLC6A2 | |
| SCHEMBL11236259 | 0.85 | HTR2B (0.42) | NPY1RNPY2RNPY4RNPY5RSLC6A2 | |
| SCHEMBL11244526 | 0.85 | HTR2B (0.42) | NPY1RNPY2RNPY4RNPY5RSLC6A2 | |
| SCHEMBL11231006 | 0.85 | TDP1 (0.50) | NPY1RNPY2RNPY4RNPY5RTDP1 | |
| SCHEMBL11231029 | 0.85 | TDP1 (0.50) | NPY1RNPY2RNPY4RNPY5RTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320137-A | Derivatives of perhydro-aza-heterocycles | CIBA-GEIGY CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |
| US-4246269-A | Antidepressant piperidinones | CIBA-GEIGY CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| US-4160837-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |