Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.64 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.62 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 7/20 | 0.55 |
| ▸ | HTT | P42858 | 6/20 | 0.55 |
| ▸ | EGFR | P00533 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | GALR3 | O60755 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260593 | 0.89 | PIK3CD (0.71) | LDHAPIK3CDPIK3R1LMNAHTT | |
| SCHEMBL11249743 | 0.86 | PIK3CD (0.73) | LDHAPIK3CDPIK3R1LMNAHTT | |
| SCHEMBL11258419 | 0.86 | LDHA (0.64) | LDHAPIK3CDPIK3R1LMNAHTT | |
| SCHEMBL11256733 | 0.86 | LDHA (0.64) | LDHAPIK3CDPIK3R1LMNAHTT | |
| SCHEMBL11251531 | 0.86 | LDHA (0.72) | LDHAPIK3CDPIK3R1LMNAHTT | |
| SCHEMBL11249387 | 0.86 | LDHA (0.68) | LDHAPIK3CDPIK3R1LMNAHTT | |
| SCHEMBL11246622 | 0.85 | PIK3CD (0.66) | LDHAPIK3CDPIK3R1LMNAHTT | |
| SCHEMBL11246662 | 0.83 | LDHA (0.64) | LDHAPIK3CDPIK3R1LMNAHTT | |
| SCHEMBL11249931 | 0.83 | SMN1; SMN2 (0.64) | LDHAPIK3CDPIK3R1LMNAHTT | |
| SCHEMBL11240638 | 0.83 | EGFR (0.68) | LDHAPIK3CDPIK3R1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |