Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 8/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1988245 | 0.84 | AKR1C3 (0.49) | AKR1C3AKR1C2SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL8862146 | 0.83 | HCAR3 (0.46) | KDM4EPOLBKMT2A | |
| SCHEMBL31702789 | 0.83 | HCAR3 (0.46) | KDM4EPOLBKMT2A | |
| SCHEMBL687106 | 0.82 | KDM4E (0.53) | AKR1C3AKR1C2SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL1990568 | 0.82 | HPSE (0.51) | AKR1C3AKR1C2SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL4294900 | 0.81 | SMN1; SMN2 (0.53) | AKR1C3AKR1C2SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL8627436 | 0.81 | HPSE (0.50) | AKR1C3AKR1C2SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL1987832 | 0.81 | PPARA (0.56) | — | |
| SCHEMBL13734817 | 0.80 | KDM4E (0.46) | AKR1C3AKR1C2APPSMN1; SMN2HSD17B10 | |
| Alcohol SCHEMBL28006228 | 0.80 | SMN1; SMN2 (0.54) | AKR1C3AKR1C2SMN1; SMN2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336360-A | IN THE PRESENCE OF A CATALYST COMPLEX | MONTECATINI EDISON S.P.A. (IT) | 1982-06-22 | — | — | US | disclosed |
| US-4187196-A | REACTING HALOGENATED TITANIUM COMPOUND WITH MAGNESIUM OR MANGANESE DIHALIDE | MONTEDISON S.P.A. (IT) | 1980-02-05 | — | — | US | disclosed |
| US-4156063-A | USING A CATALYST CONTAINING THE REACTION PRODUCT OF AN ALUMINUM COMPOUND AND AN ESTER WITH A SUPPORT CONTAINING THE REACTION PRODUCT OF A TITANIUM COMPOUND AND A MAGNESIUM OR MANGANESE BIHALIDE | Montecanti Edison, S.p.A. (IT) | 1979-05-22 | — | — | US | disclosed |
| US-4107414-A | Process for the stereoregular polymerization of alpha olefins | MONTECATINI EDISON S.P.A. (IT) | 1978-08-15 | — | — | US | disclosed |