SCHEMBL11243349

SCHEMBL11243349

[CH]=CCCCCCCCCCCCCCCC=C

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ABCC4 O15439 1/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 4/20 0.43
TRPA1 O75762 3/20 0.41
LPAR3 Q9UBY5 2/20 0.38
LMNA P02545 2/20 0.38
LPAR2 Q9HBW0 1/20 0.38
TDP1 Q9NUW8 2/20 0.34
USP2 O75604 2/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6333514 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL11256056 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL3674647 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL6335468 1.00
SCHEMBL7295537 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL25171300 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL11263505 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL21694534 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL20718786 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL29234095 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
CN-118109069-A Resin composition, cured product, and method for producing cured product 东京应化工业株式会社 2024-05-31 CN disclosed
CN-118108899-A Curable resin composition, cured product, and method for producing cured product 东京应化工业株式会社 2024-05-31 CN disclosed
WO-2023085299-A1 CATIONIC LIPID 武田薬品工業株式会社 2023-05-19 WO disclosed
EP-0002938-B1 NOVEL HETEROCYCLIC CARBOTHIOAMIDES, COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE ELI LILLY AND COMPANY (US) 1982-05-12 EP disclosed
EP-0002939-B1 NOVEL CARBOTHIOAMIDES, COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION ELI LILLY AND COMPANY (US) 1982-04-21 EP disclosed
EP-0003081-B1 THIAZOLIDINECARBOTHIOAMIDES, THEIR PREPARATION, COMPOSITIONS AND USE AS INSECTICIDES ELI LILLY AND COMPANY (US) 1981-12-30 EP disclosed
US-4289778-A SYSTEMIC INSECTICIDES ELI LILLY AND COMPANY (US) 1981-09-15 US disclosed
US-4289766-A Heterocyclic carbothioamides ELI LILLY AND COMPANY (US) 1981-09-15 US disclosed
US-4195092-A INSECTICIDES FOR TREATING MEXICAN BEAN BEETLE ELI LILLY AND COMPANY (US) 1980-03-25 US disclosed
EP-0003081-A2 Thiazolidinecarbothioamides, their preparation, compositions and use as insecticides ELI LILLY AND COMPANY (US) 1979-07-25 EP disclosed
EP-0002938-A2 Novel heterocyclic carbothioamides, compositions containing them, their preparation and use ELI LILLY AND COMPANY (US) 1979-07-11 EP disclosed
EP-0002939-A2 Novel carbothioamides, compositions containing them and their preparation ELI LILLY AND COMPANY (US) 1979-07-11 EP disclosed