SCHEMBL3674647

SCHEMBL3674647

[CH]=CCCCCCCC=C

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ABCC4 O15439 1/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 4/20 0.43
TRPA1 O75762 3/20 0.41
LPAR3 Q9UBY5 2/20 0.38
LMNA P02545 2/20 0.38
LPAR2 Q9HBW0 1/20 0.38
TDP1 Q9NUW8 2/20 0.34
USP2 O75604 2/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6333514 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL11256056 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL6335468 1.00
SCHEMBL11243349 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL7295537 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL25171300 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL11263505 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL21694534 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL20718786 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL29234095 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118136960-B Electrolyte and battery 深圳欣界能源科技有限公司 2024-07-16 CN claimed
CN-118136960-A Electrolyte and battery 深圳欣界能源科技有限公司 2024-06-04 CN claimed
CN-117844411-A Aqueous emulsion polymer binder of secondary battery and preparation method thereof 杨志雄 2024-04-09 CN claimed
CN-116370439-A Vanilla transdermal patch, and preparation method and application thereof 江苏山信药业有限公司 2023-07-04 CN claimed
CN-106565870-A Olefin polymerization catalyst and preparation method thereof, olefin polymerization catalyst system and applications thereof, and polyolefin resin preparation method 中国科学院化学研究所 2017-04-19 CN claimed
CN-118136960-B Electrolyte and battery 深圳欣界能源科技有限公司 2024-07-16 CN disclosed
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
CN-118136960-A Electrolyte and battery 深圳欣界能源科技有限公司 2024-06-04 CN disclosed
CN-117844411-A Aqueous emulsion polymer binder of secondary battery and preparation method thereof 杨志雄 2024-04-09 CN disclosed
CN-114736434-B Preparation method of PTFE fastener with metal detectable function 浙江科赛新材料科技有限公司 2023-11-17 CN disclosed
CN-116370439-A Vanilla transdermal patch, and preparation method and application thereof 江苏山信药业有限公司 2023-07-04 CN disclosed
CN-105555817-B Use of gel-like polymer compositions obtainable by polymerization of acid group-containing monomers in the presence of polyether compounds in formulations for dishwashing 巴斯夫欧洲公司 2019-09-03 CN disclosed
CN-1114834-A antidiabetic agent OTSUKA PHARMA CO LTD (JP) 1996-01-10 CN disclosed
US-5306719-A Cardiotonic agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-04-26 US disclosed
EP-0255134-B1 CARBOSTYRIL DERIVATIVES AND SALTS THEREOF, PROCESS FOR PREPARING THEM, AND CARDIOTONIC COMPOSITION CONTAINING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-03-03 EP disclosed
US-5071856-A CARBOSTYRIL DERIVATIVES AND SALTS THEREOF OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-12-10 US disclosed
US-4886809-A CARDIOTONIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-12-12 US disclosed
US-4845100-A WITH HYPOTENSIVE AND ANTIINFLAMMATORY ACTIVITY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-07-04 US disclosed
EP-0255134-A2 Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-02-03 EP disclosed
EP-0202760-A2 Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-11-26 EP disclosed