Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | IL2 | P60568 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 8/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241321 | 0.90 | MEN1 (0.48) | MEN1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8659039 | 0.86 | NPC1 (0.47) | MEN1LMNAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL11253045 | 0.83 | TDP1 (0.59) | MEN1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL11241860 | 0.82 | TRPA1 (0.46) | MEN1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL11390176 | 0.82 | ATM (0.45) | MEN1LMNAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL11237773 | 0.81 | JAK2 (0.51) | MEN1LMNAHTTKMT2AMAPT | |
| SCHEMBL11242482 | 0.81 | NPC1 (0.45) | MEN1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL11244282 | 0.80 | NPC1 (0.50) | MAPTNPSR1TLR8TLR7KDM4E | |
| SCHEMBL11250296 | 0.78 | KMT2A (0.43) | MEN1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL10908649 | 0.78 | NPC1 (0.45) | MEN1LMNAKMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |