Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241762 | 0.91 | KMT2A (0.68) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL18489560 | 0.88 | TSHR (0.65) | KMT2AMEN1HDAC3HDAC1HDAC2 | |
| SCHEMBL28233208 | 0.87 | TSHR (0.56) | KMT2AMEN1HDAC3HDAC1HDAC2 | |
| SCHEMBL17502700 | 0.87 | KMT2A (0.56) | KMT2AMEN1TSHRL3MBTL1TDP1 | |
| SCHEMBL7488349 | 0.86 | KMT2A (0.67) | KMT2AMEN1HDAC3HDAC1HDAC2 | |
| SCHEMBL17502664 | 0.85 | KDM4E (0.59) | KMT2AMEN1TSHRL3MBTL1TDP1 | |
| SCHEMBL12392710 | 0.85 | CYP1A2 (0.60) | KMT2ATSHRL3MBTL1TDP1NPC1 | |
| SCHEMBL31198163 | 0.85 | L3MBTL1 (0.60) | TSHRL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL7285937 | 0.85 | KMT2A (0.62) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL7285948 | 0.85 | KMT2A (0.62) | KMT2AMEN1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342875-A | STABILIZERS FOR OLEFIN POLYMERS | CINCINNATI-MILACRON, INC. (US) | 1982-08-03 | — | — | US | disclosed |