Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23538130 | 0.79 | SYK (0.45) | SYKS1PR4MRGPRX4TSHRCYP1A2 | |
| SCHEMBL29638125 | 0.79 | SYK (0.78) | SYKHTR1ADRD2 | |
| SCHEMBL159323 | 0.79 | SYK (0.78) | SYKHTR1ADRD2 | |
| SCHEMBL27299219 | 0.78 | TSHR (0.47) | S1PR4MRGPRX4NPC1TP53MAPT | |
| SCHEMBL21835275 | 0.78 | SYK (0.52) | SYKS1PR4MRGPRX4NPC1TP53 | |
| SCHEMBL29945002 | 0.78 | SYK (0.52) | SYKS1PR4MRGPRX4NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL23859934 | 0.78 | SYK (0.76) | SYKHTR1ADRD2 | |
| SCHEMBL2702047 | 0.78 | SYK (0.52) | SYKS1PR4MRGPRX4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6239858 | 0.78 | SYK (0.76) | SYKTP53SMN1; SMN2HTR1ADRD2 | |
| SCHEMBL29944991 | 0.78 | SYK (0.52) | SYKS1PR4MRGPRX4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332944-A | Compositions and use | ZOECON CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |