Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.76 |
| ▸ | ERBB2 | P04626 | 10/20 | 0.51 |
| ▸ | EGFR | P00533 | 8/20 | 0.51 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.51 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638125 | 0.98 | SYK (0.78) | SYKERBB2EGFRERBB3ERBB4 | |
| SCHEMBL159323 | 0.98 | SYK (0.78) | SYKERBB2EGFRERBB3ERBB4 | |
| Hydrochloric Acid SCHEMBL6239858 | 0.97 | SYK (0.76) | SYKERBB2EGFRERBB3ERBB4 | |
| SCHEMBL17601189 | 0.87 | SYK (1.00) | SYKERBB2EGFRERBB3ERBB4 | |
| SCHEMBL30623239 | 0.87 | SYK (1.00) | SYKERBB2EGFRERBB3ERBB4 | |
| SCHEMBL27097004 | 0.84 | SYK (0.58) | SYKERBB2EGFRERBB3ERBB4 | |
| SCHEMBL30729948 | 0.84 | SYK (0.58) | SYKERBB2EGFRERBB3ERBB4 | |
| SCHEMBL21340419 | 0.82 | SYK (0.58) | SYKERBB2EGFRERBB3ERBB4 | |
| SCHEMBL29568574 | 0.82 | SYK (0.58) | SYKERBB2EGFRERBB3ERBB4 | |
| SCHEMBL4028096 | 0.81 | SYK (0.54) | SYKERBB2EGFRERBB3ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195206-A1 | POLYMORPHIC FORMS AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2021-09-30 | — | — | WO | disclosed |