Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | IL6 | P05231 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222751 | 0.78 | TSHR (0.49) | ALDH1A1MAPTTDP1 | |
| SCHEMBL11226368 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTTDP1 | |
| SCHEMBL30152700 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPTTDP1 | |
| SCHEMBL1768922 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPTTDP1 | |
| SCHEMBL18863552 | 0.70 | ALDH1A1 (0.43) | ALDH1A1TDP1 | |
| SCHEMBL1999849 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TDP1 | |
| SCHEMBL30627320 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TDP1 | |
| SCHEMBL1995565 | 0.69 | TDP1 (0.47) | ALDH1A1TDP1 | |
| SCHEMBL1459395 | 0.69 | TSHR (0.53) | ALDH1A1TDP1 | |
| SCHEMBL6515 | 0.69 | TDP1 (0.47) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007243-B1 | 2-ARYL-1,3-CYCLOHEXANEDIONE COMPOUNDS AND ALKALI METAL SALTS, AMMONIUM SALTS AND ENOL ESTERS THEREOF, COMPOSITION AND METHOD OF CONTROLLING ACARINA ECTOPARASITES ON WARMBLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4257858-A | REACTING A CYCLOHEXA-1,3-DIONE-2-DIAZIDE WITH AN ARYL COMPOUND | UNION CARBIDE CORPORATION (US) | 1981-03-24 | — | — | US | disclosed |
| US-4256658-A | CYCLIZATION, BASIC CATALYST | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4256657-A | CYCLIZATION, ACID CATALYST | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4209532-A | Biocidal 2-aryl-1,3-cyclohexane dione compounds and alkali metal and ammonium salts thereof | UNION CARBIDE CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| EP-0007243-A1 | 2-Aryl-1,3-cyclohexanedione compounds and alkali metal salts, ammonium salts and enol esters thereof, composition and method of controlling acarina ectoparasites on warmblooded animals | UNION CARBIDE CORPORATION (US) | 1980-01-23 | — | — | EP | disclosed |
| US-4175135-A | Method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animal an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound, and alkali metal salts, ammonium salts and enol esters thereof | UNION CARBIDE CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |