Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 8/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.65 |
| ▸ | PGR | P06401 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 8/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | BLM | P54132 | 4/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.60 |
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30171328 | 0.88 | SHBG (0.71) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL13146616 | 0.88 | SHBG (0.71) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Spriolactone SCHEMBL30112125 | 0.85 | SHBG (0.67) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Spriolactone SCHEMBL8259555 | 0.85 | SHBG (0.67) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Spriolactone SCHEMBL20459223 | 0.85 | SHBG (0.67) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Spriolactone SCHEMBL10786113 | 0.85 | SHBG (0.67) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Spriolactone SCHEMBL18218188 | 0.85 | SHBG (0.67) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Spriolactone SCHEMBL14285054 | 0.85 | SHBG (0.67) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Spriolactone SCHEMBL8260326 | 0.85 | SHBG (0.67) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL12085097 | 0.83 | SHBG (0.68) | SHBGNR3C1PGRALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3371238-A1 | THERMOFORMABLE DUAL NETWORK HYDROGEL COMPOSITIONS | Lubrizol Advanced Materials, Inc. (US) | 2018-09-12 | — | — | EP | disclosed |
| WO-2017079248-A1 | THERMOFORMABLE DUAL NETWORK HYDROGEL COMPOSITIONS | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2017-05-11 | — | — | WO | disclosed |
| US-4317817-A | SKIN DISORDERS; ACEME; ENZYME INHIBITORS | RICHARDSON-MERRELL INC. (US) | 1982-03-02 | — | — | US | disclosed |