SCHEMBL11244290

SCHEMBL11244290

CC(C)(CF)/C(Cn1cncn1)=N\O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.34
CYP19A1 P11511 6/20 0.34
CYP3A4 P08684 3/20 0.33
CYP2C19 P33261 2/20 0.33
EGLN3 Q9H6Z9 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HSP90AA1 P07900 2/20 0.33
ALDH1A1 P00352 1/20 0.32
UGT1A4 P22310 1/20 0.32
PDE4D Q08499 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11244294 1.00 FDPS (0.34) FDPSCYP19A1CYP3A4CYP2C19EGLN3
SCHEMBL11233552 0.86 CYP3A4 (0.35) FDPSCYP19A1CYP3A4CYP2C19EGLN3
SCHEMBL11233553 0.86 CYP3A4 (0.35) FDPSCYP19A1CYP3A4CYP2C19EGLN3
SCHEMBL11242336 0.84 CYP3A4 (0.35) FDPSCYP19A1CYP3A4CYP2C19EGLN3
SCHEMBL11242334 0.84 CYP3A4 (0.35) FDPSCYP19A1CYP3A4CYP2C19EGLN3
SCHEMBL11238618 0.83 FDPS (0.38) FDPSCYP19A1CYP3A4CYP2C19EGLN3
SCHEMBL11238616 0.83 FDPS (0.38) FDPSCYP19A1CYP3A4CYP2C19EGLN3
SCHEMBL11234157 0.82 CYP19A1 (0.33) FDPSCYP19A1CYP3A4CYP2C19EGLN3
SCHEMBL11234160 0.82 CYP19A1 (0.33) FDPSCYP19A1CYP3A4CYP2C19EGLN3
SCHEMBL11236102 0.82 CYP19A1 (0.33) FDPSCYP19A1CYP3A4CYP2C19EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4344953-A INSECTICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1982-08-17 US disclosed
EP-0005249-B1 SUBSTITUTED ALKANYL-AZOLYL CARBAMATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES, ACARICIDES AND NEMATOCIDES BAYER AG (DE) 1981-09-02 EP disclosed
EP-0005249-A2 Substituted alkanyl-azolyl carbamates, process for their preparation and their use as insecticides, acaricides and nematocides BAYER AG (DE) 1979-11-14 EP disclosed