Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245362 | 0.86 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL11242617 | 0.83 | HCAR2 (0.54) | TSHRCYP3A4ATMTDP1CA1 | |
| SCHEMBL20359743 | 0.81 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL19456761 | 0.78 | TSHR (0.87) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL1480795 | 0.78 | TSHR (0.87) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL28789728 | 0.77 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL990755 | 0.77 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL27821517 | 0.77 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL753507 | 0.77 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL4369137 | 0.76 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323363-A | DISPERSE DYE USED ON POLYESTERS MIXED WITH CELLULOSE | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-04-06 | — | — | US | disclosed |