Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070296 | 0.83 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL184856 | 0.83 | TSHR (0.60) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28454119 | 0.80 | TSHR (0.61) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL20359743 | 0.79 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10306277 | 0.79 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL6401315 | 0.76 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11244296 | 0.76 | TSHR (0.60) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL6046946 | 0.75 | — | — | |
| SCHEMBL74390 | 0.74 | TSHR (0.73) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28921629 | 0.74 | MAPT (0.40) | TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396891-B2 | Two-component coating composition and method of preparation | ROHM AND HAAS COMPANY (US) | 2008-07-08 | — | — | US | claimed |
| EP-2069569-A2 | FLAME RETARDED TEXTILE PRODUCTS AND A METHOD OF MAKING THE SAME | Albermarle Corporation (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008030792-A2 | FLAME RETARDED TEXTILE PRODUCTS AND A METHOD OF MAKING THE SAME | ALBEMARLE CORPORATION (US) | 2008-03-13 | — | — | WO | disclosed |