SCHEMBL11244476

SCHEMBL11244476

CN(C)CCOc1ccccc1CCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.74
DRD1 P21728 1/20 0.74
DRD4 P21917 1/20 0.74
DRD5 P21918 1/20 0.74
HRH1 P35367 2/20 0.63
HTR1A P08908 1/20 0.60
ABCB1 P08183 1/20 0.56
HTR7 P34969 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11266708 0.98 DRD2 (0.72) DRD2DRD1DRD4DRD5HRH1
SCHEMBL11253910 0.92 HRH1 (0.75) DRD2DRD1DRD4DRD5HRH1
Hydrochloric Acid SCHEMBL11256997 0.91 HRH1 (0.73) DRD2DRD1DRD4DRD5HRH1
SCHEMBL11253611 0.91 HRH1 (0.68) DRD2DRD1DRD4DRD5HRH1
SCHEMBL8702877 0.91 DRD2 (0.70) DRD2DRD1DRD4DRD5HRH1
Hydrochloric Acid SCHEMBL8707049 0.89 DRD2 (0.68) DRD2DRD1DRD4DRD5HRH1
SCHEMBL11260136 0.89 HRH1 (0.67) DRD2DRD1DRD4DRD5HRH1
SCHEMBL11257755 0.89 HRH1 (0.67) DRD2DRD1DRD4DRD5HRH1
SCHEMBL11254706 0.89 HRH1 (0.67) DRD2DRD1DRD4DRD5HRH1
SCHEMBL11260586 0.88 DRD2 (0.58) DRD2DRD1DRD4DRD5HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0001759-B1 (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES MITSUBISHI KASEI CORPORATION (JP) 1981-12-30 EP claimed
US-4220603-A ANTICOAGULANTS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1980-09-02 US claimed
EP-0001759-A1 (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances MITSUBISHI KASEI CORPORATION (JP) 1979-05-16 EP claimed
US-4323568-A INHIBIT PLATELET AGGREGATION MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1982-04-06 US disclosed
EP-0001759-B1 (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES MITSUBISHI KASEI CORPORATION (JP) 1981-12-30 EP disclosed
US-4220603-A ANTICOAGULANTS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1980-09-02 US disclosed
EP-0001759-A1 (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances MITSUBISHI KASEI CORPORATION (JP) 1979-05-16 EP disclosed