Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 10/20 | 0.61 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.60 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FABP2 | P12104 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14247143 | 0.76 | NOD1 (1.00) | NOD1CXCL8NOD2GAAALDH3A1 | |
| SCHEMBL11258166 | 0.71 | SMN1; SMN2 (0.46) | AKR1C3AKR1C2PTGS2TSHRPTGS1 | |
| SCHEMBL27733700 | 0.70 | RECQL (0.56) | NOD1CXCL8NOD2ALDH1A1HPGD | |
| SCHEMBL14247102 | 0.69 | NOD1 (0.69) | NOD1CXCL8NOD2GAAALDH3A1 | |
| SCHEMBL27713335 | 0.69 | PPARG (0.58) | NOD1NOD2ALDH3A1ALDH1A1HPGD | |
| SCHEMBL10643033 | 0.69 | PI4KB (0.61) | NOD1CXCL8PI4KBALDH1A1HPGD | |
| SCHEMBL29399999 | 0.69 | NOD1 (1.00) | NOD1CXCL8NOD2GAAALDH3A1 | |
| SCHEMBL10107599 | 0.69 | NOD1 (1.00) | NOD1CXCL8NOD2GAAALDH3A1 | |
| SCHEMBL27733864 | 0.68 | PPARG (0.59) | NOD1NOD2 | |
| SCHEMBL27713493 | 0.68 | PPARG (0.43) | ALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316021-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4243813-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4196125-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4118573-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4018790-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |