Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 2/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | PPP1CC | P36873 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19323685 | 0.92 | PPM1B (0.59) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL19318639 | 0.92 | PPM1B (0.59) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL11241112 | 0.92 | PPM1B (0.59) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL14874442 | 0.91 | PPM1B (0.55) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL14189737 | 0.91 | PPM1B (0.55) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL14874553 | 0.91 | PPM1B (0.55) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL6410025 | 0.83 | PPM1B (0.49) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL10050521 | 0.83 | PPM1B (0.52) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL14189734 | 0.83 | PPM1B (0.52) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL14189733 | 0.83 | PPM1B (0.52) | PPM1BPTPN1PPP1CCALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349552-A | TREATMENT OF CANCER | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-09-14 | — | — | US | disclosed |
| EP-0010941-B1 | 5-FLUOROURACIL DERIVATIVES, PREPARATION THEREOF AND THEIR PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-12 | — | — | EP | disclosed |
| EP-0010941-A1 | 5-Fluorouracil derivatives, preparation thereof and their pharmaceutical compositions | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-05-14 | — | — | EP | disclosed |