Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14874553 | 0.91 | PPM1B (0.55) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL14189737 | 0.91 | PPM1B (0.55) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL14874442 | 0.91 | PPM1B (0.55) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL9939091 | 0.87 | PPM1B (0.42) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL12131803 | 0.85 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL11244590 | 0.83 | PPM1B (0.62) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL14189734 | 0.83 | PPM1B (0.52) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL10050521 | 0.83 | PPM1B (0.52) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL14189733 | 0.83 | PPM1B (0.52) | PPM1BPTPN1PPP1CCALDH1A1MAPT | |
| SCHEMBL8400471 | 0.83 | PPM1B (0.52) | PPM1BPTPN1PPP1CCALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581511-A1 | CCR8 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004058736-A1 | CCR8 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | disclosed |