Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 11/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253869 | 0.97 | TSHR (0.44) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL20819823 | 0.97 | TSHR (0.44) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL38663510 | 0.97 | TSHR (0.44) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL32669051 | 0.97 | TSHR (0.44) | TSHRTHRBFDPSGGPS1SMPD1 | |
| Fluoride SCHEMBL29288700 | 0.95 | TSHR (0.42) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL594044 | 0.91 | TSHR (0.35) | TSHRTHRBFDPS | |
| SCHEMBL16497589 | 0.87 | TSHR (0.33) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL25274570 | 0.85 | TSHR (0.38) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL25272836 | 0.85 | TSHR (0.38) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL25278222 | 0.85 | TSHR (0.38) | TSHRTHRBFDPSGGPS1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563186-B | Method for producing modified conjugated diene polymer and method for producing polymer composition | 住友化学株式会社 | 2022-04-15 | — | — | CN | disclosed |
| WO-2019055028-A1 | PARTICLES, COMPOSITIONS, AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS | KALA PHARMACEUTICALS, INC. (US) | 2019-03-21 | — | — | WO | disclosed |
| US-4315032-A | ANTITHROMBOGENIC AGENTS, ANTIULCER AGENTS | TEITIN LIMITED (JP) | 1982-02-09 | — | — | US | disclosed |
| US-4273770-A | CORTICOIDS, ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1981-06-16 | — | — | US | disclosed |
| EP-0019475-A2 | Process for preparing adjacently disubstituted ketones, novel prostaglandins E1 and anti-thrombotic compositions containing them | TEIJIN LIMITED (JP) | 1980-11-26 | — | — | EP | disclosed |