Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244658 | 0.91 | TSHR (0.39) | TSHRTHRBFDPS | |
| SCHEMBL38663510 | 0.88 | TSHR (0.44) | TSHRTHRBFDPS | |
| SCHEMBL20819823 | 0.88 | TSHR (0.44) | TSHRTHRBFDPS | |
| SCHEMBL11253869 | 0.88 | TSHR (0.44) | TSHRTHRBFDPS | |
| SCHEMBL32669051 | 0.88 | TSHR (0.44) | TSHRTHRBFDPS | |
| Fluoride SCHEMBL29288700 | 0.86 | TSHR (0.42) | TSHRTHRBFDPS | |
| SCHEMBL14779120 | 0.81 | TSHR (0.35) | TSHRLMNAESR1ESR2THRB | |
| SCHEMBL594532 | 0.80 | ALDH1A1 (0.35) | TSHRALDH1A1TDP1 | |
| SCHEMBL16497589 | 0.78 | TSHR (0.33) | TSHRLMNATHRBFDPSALDH1A1 | |
| SCHEMBL10839797 | 0.77 | TSHR (0.37) | TSHRTHRBFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619935-A | Method for selectively protecting ortho-phenolic hydroxyl groups of tea polyphenol | 浙江大学 | 2024-09-10 | — | — | CN | claimed |
| CN-118434672-A | Method for removing water from bis (fluorosulfonyl) imide solution | 法国特种经营公司 | 2024-08-02 | — | — | CN | claimed |
| CN-115043895-A | PNU-159682 and preparation method of intermediate thereof | 戊言医药科技（上海）有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-110698527-B | Preparation method of high-purity hydrocortisone-17-valerate | 湖南新合新生物医药有限公司 | 2022-08-26 | — | — | CN | claimed |
| US-20180280568-A1 | POLY(THIOKETAL URETHANE) SCAFFOLDS AND METHODS OF USE | VANDERBILT UNIVERSITY | 2018-10-04 | — | — | US | claimed |
| EP-3362107-A1 | POLY(THIOKETAL-URETHANE) SCAFFOLDS AND METHODS OF USE | Vanderbilt University (US) | 2018-08-22 | — | — | EP | claimed |
| WO-2017066670-A1 | POLY(THIOKETAL-URETHANE) SCAFFOLDS AND METHODS OF USE | VANDERBILT UNIVERSITY (US) | 2017-04-20 | — | — | WO | claimed |
| EP-3036264-A1 | HIGH MOLECULAR WEIGHT POLYMERS HAVING HIGH OLEFIN CONTENT | Henkel IP & Holding GmbH (DE) | 2016-06-29 | — | — | EP | claimed |
| WO-2015024236-A1 | HIGH MOLECULAR WEIGHT POLYMERS HAVING HIGH OLEFIN CONTENT | HENKEL CORPORATION (US) | 2015-02-26 | — | — | WO | claimed |
| WO-2004000976-A2 | FUEL ADDITIVE AND METHOD THEREFOR | MILLENIUM FUELS, USA LLC (US) | 2003-12-31 | — | — | WO | claimed |
| US-6514299-B1 | Blends of acyclic alcohols and ethers, used to improve octane ratings of gasoline fuels; pollution control | MILLENNIUM FUELS USA, LLC | 2003-02-04 | — | — | US | claimed |
| US-4252738-A | 1,2-Halohydrincarboxylic acid esters and a process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | claimed |
| EP-4719385-A2 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINES AS ANTI-INFECTIOUS AGENTS | University of Vermont and State Agricultural College (US) | 2026-04-08 | — | — | EP | disclosed |
| US-12583861-B2 | Derivatives of imidazo[4,5-d]pyridazine, their preparation and their therapeutic application | SANOFI (FR) | 2026-03-24 | — | — | US | disclosed |
| EP-4288438-B1 | DERIVATIVES OF IMIDAZO[4,5-D]PYRIDAZINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI SA (FR) | 2026-02-18 | — | — | EP | disclosed |
| WO-2025031923-A1 | IMIDAZO[4,5-D]PYRIDAZINE COMPOUNDS AND CONJUGATES THEREOF, THEIR PREPARATION, AND THEIR THERAPEUTIC APPLICATIONS | SANOFI (FR) | 2025-02-13 | — | — | WO | disclosed |
| US-4315032-A | ANTITHROMBOGENIC AGENTS, ANTIULCER AGENTS | TEITIN LIMITED (JP) | 1982-02-09 | — | — | US | disclosed |
| US-4252738-A | 1,2-Halohydrincarboxylic acid esters and a process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |
| EP-0019475-A2 | Process for preparing adjacently disubstituted ketones, novel prostaglandins E1 and anti-thrombotic compositions containing them | TEIJIN LIMITED (JP) | 1980-11-26 | — | — | EP | disclosed |
| US-4181720-A | Corticosteroid antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1980-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583861-B2 | Derivatives of imidazo[4,5-d]pyridazine, their preparation and their therapeutic application | TLR7, TLR8, TLR6 | TSHR 672/4885LMNA 813/4885ESR1 2938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.