Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244677 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2EPHX1TSHRMEN1KMT2A | |
| SCHEMBL4586198 | 0.93 | SMN1; SMN2 (0.55) | SMN1; SMN2EPHX1TSHRMEN1KMT2A | |
| SCHEMBL4587111 | 0.93 | EPHX1 (0.71) | SMN1; SMN2EPHX1TSHRMEN1KMT2A | |
| SCHEMBL4586209 | 0.93 | EPHX1 (0.71) | SMN1; SMN2EPHX1TSHRMEN1KMT2A | |
| SCHEMBL7769494 | 0.93 | EPHX1 (0.71) | SMN1; SMN2EPHX1TSHRMEN1KMT2A | |
| SCHEMBL6942870 | 0.88 | MEN1 (0.57) | SMN1; SMN2EPHX1TSHRMEN1KMT2A | |
| SCHEMBL6942864 | 0.88 | MEN1 (0.57) | SMN1; SMN2EPHX1TSHRMEN1KMT2A | |
| SCHEMBL4586041 | 0.87 | EPHX1 (0.63) | SMN1; SMN2EPHX1TSHRMEN1KMT2A | |
| SCHEMBL14064432 | 0.87 | EPHX1 (0.63) | SMN1; SMN2EPHX1TSHRMEN1KMT2A | |
| SCHEMBL4585957 | 0.87 | EPHX1 (0.63) | SMN1; SMN2EPHX1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4340728-A | ANTITUMOR AGENT OF 5-FLUORO URIDINE OR URACIL DERIVATIVE | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-07-20 | — | — | US | disclosed |