Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942870 | 1.00 | MEN1 (0.57) | MEN1KMT2ATSHRSMN1; SMN2EPHX1 | |
| SCHEMBL11244677 | 0.88 | SMN1; SMN2 (0.62) | MEN1KMT2ATSHRSMN1; SMN2EPHX1 | |
| SCHEMBL11244673 | 0.88 | SMN1; SMN2 (0.62) | MEN1KMT2ATSHRSMN1; SMN2EPHX1 | |
| SCHEMBL4587111 | 0.85 | EPHX1 (0.71) | MEN1KMT2ATSHRSMN1; SMN2EPHX1 | |
| SCHEMBL7769494 | 0.85 | EPHX1 (0.71) | MEN1KMT2ATSHRSMN1; SMN2EPHX1 | |
| SCHEMBL4586209 | 0.85 | EPHX1 (0.71) | MEN1KMT2ATSHRSMN1; SMN2EPHX1 | |
| SCHEMBL7259180 | 0.83 | MEN1 (0.51) | MEN1KMT2ATSHRSMN1; SMN2EPHX1 | |
| SCHEMBL4586198 | 0.82 | SMN1; SMN2 (0.55) | MEN1KMT2ATSHRSMN1; SMN2EPHX1 | |
| SCHEMBL5705785 | 0.81 | EPHX1 (0.43) | MEN1KMT2ATSHRSMN1; SMN2EPHX1 | |
| SCHEMBL2625542 | 0.80 | EPHX1 (0.70) | MEN1KMT2ASMN1; SMN2EPHX1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155002-A4 | METHOD OF SYNTHESIZING BARBITURIC ACID DERIVATIVES AND THEIR USE FOR THE SYNTHESIS OF CHEMICAL LIBRARIES | TRANSTECH PHARMA INC (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1155002-A1 | METHOD OF SYNTHESIZING BARBITURIC ACID DERIVATIVES AND THEIR USE FOR THE SYNTHESIS OF CHEMICAL LIBRARIES | TransTech Pharma Inc. (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000046211-A1 | METHOD OF SYNTHESIZING BARBITURIC ACID DERIVATIVES AND THEIR USE FOR THE SYNTHESIS OF CHEMICAL LIBRARIES | TRANSTECH PHARMA (US) | 2000-08-10 | — | — | WO | disclosed |
| US-4340728-A | ANTITUMOR AGENT OF 5-FLUORO URIDINE OR URACIL DERIVATIVE | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-07-20 | — | — | US | disclosed |