Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 12/20 | 0.45 |
| ▸ | CNR1 | P21554 | 8/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131241 | 0.86 | CNR2 (0.48) | KDM4EHPGDALDH1A1POLBCNR2 | |
| SCHEMBL10901358 | 0.86 | CNR2 (0.51) | KDM4EHPGDALDH1A1POLBCNR2 | |
| SCHEMBL9750686 | 0.85 | HPGD (0.51) | KDM4EHPGDALDH1A1POLBCNR2 | |
| SCHEMBL11279057 | 0.84 | ALDH1A1 (0.53) | KDM4EHPGDALDH1A1POLBCNR2 | |
| SCHEMBL9815397 | 0.83 | EGFR (0.48) | KDM4EHPGDALDH1A1CYP2C19MEN1 | |
| SCHEMBL10376439 | 0.81 | ALDH1A1 (0.54) | KDM4EHPGDALDH1A1POLBCNR2 | |
| SCHEMBL11492278 | 0.80 | PTGDR2 (0.45) | KDM4EHPGDALDH1A1POLBTSHR | |
| SCHEMBL9198796 | 0.79 | ALDH1A1 (0.59) | KDM4EHPGDALDH1A1POLBCNR2 | |
| SCHEMBL9195261 | 0.78 | ALDH1A1 (0.56) | KDM4EHPGDALDH1A1POLBCNR2 | |
| SCHEMBL3144221 | 0.78 | CNR2 (0.39) | KDM4EHPGDALDH1A1POLBCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4334072-A | CHROMOGENS, LEUCO DYES | APPLETON PAPERS INC. (US) | 1982-06-08 | — | — | US | disclosed |
| US-4275206-A | CHROMOGENS FOR RECORDING AND MARKING SYSTEMS | APPLETON PAPERS INC. (US) | 1981-06-23 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4232887-A | PRESSURE SENSITIVE AND HEAT SENSITIVE ELEMENTS FOR RECORDING | APPLETON PAPERS INC. (US) | 1980-11-11 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |
| US-4016174-A | USED IN PRESSURE SENSITIVE RECORD MATERIALS AND MANIFOLD MARKING SYSTEMS | NCR CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |