Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PRNP | P04156 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | SCD | O00767 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 8/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654575 | 0.81 | TDP1 (0.79) | TDP1POLBKMT2AALDH1A1LMNA | |
| SCHEMBL10648666 | 0.78 | TDP1 (0.54) | TDP1POLBKMT2AALDH1A1LMNA | |
| SCHEMBL12038476 | 0.78 | RXFP1 (0.64) | TDP1POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL561348 | 0.77 | KMT2A (1.00) | TDP1POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL23203393 | 0.77 | KMT2A (1.00) | TDP1POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL23804131 | 0.77 | KMT2A (1.00) | TDP1POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL7824955 | 0.77 | KMT2A (1.00) | TDP1POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL19816485 | 0.77 | KMT2A (1.00) | TDP1POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL1134681 | 0.77 | KMT2A (1.00) | TDP1POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL8923831 | 0.77 | ESR1 (0.45) | ALDH1A1LMNAESR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309407-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANTI-ARTERIOSCLEROTIC | A. NATTERMANN & CIE. GMBH (DE) | 1982-01-05 | — | — | US | claimed |