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SCHEMBL11244930

SCHEMBL11244930

CC(C)(C)c1cc(CCCCC(=O)NCCCCCCNC(=O)CCCCc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(C(C)(C)C)c1O

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 4/20 0.67
▸ KMT2A Q03164 2/20 0.67
▸ MEN1 O00255 1/20 0.54
▸ MAOA P21397 1/20 0.47
▸ ACHE P22303 1/20 0.47
▸ MAOB P27338 1/20 0.47
▸ CNR1 P21554 4/20 0.47
▸ CNR2 P34972 3/20 0.47
▸ LMNA P02545 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ GSK3B P49841 2/20 0.45
▸ HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11250976 0.96 GAA (0.68) GAAKMT2AMEN1MAOAACHE
SCHEMBL21984935 0.93 GAA (0.73) GAAKMT2AMEN1MAOAACHE
SCHEMBL11257157 0.92 GAA (0.79) GAAKMT2AMEN1MAOAACHE
SCHEMBL11667488 0.92 GAA (0.79) GAAKMT2AMEN1MAOAACHE
SCHEMBL77798 0.92 GAA (0.79) GAAKMT2AMEN1MAOAACHE
SCHEMBL7244694 0.92 GAA (0.79) GAAKMT2AMEN1MAOAACHE
SCHEMBL9556831 0.91 GAA (0.60) GAAKMT2AMEN1CNR1CNR2
SCHEMBL9008415 0.90 GAA (0.77) GAAKMT2AMEN1MAOAACHE
SCHEMBL11703395 0.90 GAA (0.72) GAAKMT2AMEN1MAOAACHE
SCHEMBL1149604 0.90 GAA (0.81) GAAKMT2AMEN1MAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4341879-A Polyphenylene ether resin composition having improved heat stability and impact strength MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1982-07-27 — — US disclosed