Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | TP53 | P04637 | 1/20 | 0.76 |
| ▸ | AURKA | O14965 | 2/20 | 0.73 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.62 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11254237 | 0.99 | ALDH1A1 (0.80) | ALDH1A1KDM4ESMN1; SMN2RXFP1MAPT | |
| SCHEMBL31307884 | 0.92 | MAPT (0.70) | ALDH1A1KDM4ESMN1; SMN2RXFP1MAPT | |
| SCHEMBL23494012 | 0.92 | MAPT (0.70) | ALDH1A1KDM4ESMN1; SMN2RXFP1MAPT | |
| SCHEMBL23493878 | 0.91 | MAPT (0.74) | ALDH1A1KDM4ESMN1; SMN2RXFP1MAPT | |
| SCHEMBL31307789 | 0.91 | MAPT (0.74) | ALDH1A1KDM4ESMN1; SMN2RXFP1MAPT | |
| SCHEMBL31307858 | 0.90 | MAPT (0.79) | ALDH1A1KDM4ESMN1; SMN2RXFP1MAPT | |
| SCHEMBL529953 | 0.90 | MAPT (0.67) | ALDH1A1KDM4ESMN1; SMN2RXFP1MAPT | |
| SCHEMBL23494116 | 0.90 | MAPT (0.79) | ALDH1A1KDM4ESMN1; SMN2RXFP1MAPT | |
| SCHEMBL27434387 | 0.88 | MAPT (0.76) | ALDH1A1KDM4ESMN1; SMN2RXFP1MAPT | |
| SCHEMBL23575505 | 0.86 | MAPT (0.68) | ALDH1A1KDM4ESMN1; SMN2RXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343804-A | 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds | A. H. ROBINS COMPANY, INC. (US) | 1982-08-10 | — | — | US | disclosed |