Propylene Oxide

Propylene Oxide

SCHEMBL11245052

CC1CO1.CCCCCCCCNCCCCCCCC

nearest known ligand 0.59

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
TSHR P16473 2/20 0.59
S1PR2 O95136 5/20 0.44
S1PR4 O95977 5/20 0.44
S1PR1 P21453 5/20 0.44
S1PR3 Q99500 5/20 0.44
S1PR5 Q9H228 1/20 0.44
EPHX1 P07099 3/20 0.43
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
ADH1B P00325 1/20 0.43
ADH1C P00326 1/20 0.43
ADH1A P07327 1/20 0.43
ADH4 P08319 1/20 0.43
ADH7 P40394 1/20 0.43
SIGMAR1 Q99720 2/20 0.39
EBP Q15125 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Oxide SCHEMBL28348097 0.91 ALDH1A1 (0.50) ALDH1A1TSHRS1PR2S1PR4S1PR1
Phosphoric Acid SCHEMBL11779241 0.89 S1PR1 (0.58) ALDH1A1TSHRS1PR2S1PR4S1PR1
Heptane SCHEMBL11710497 0.85 ALDH1A1 (0.59) ALDH1A1TSHREPHX1SIGMAR1EBP
SCHEMBL22915556 0.80 TSHR (0.93) ALDH1A1TSHRS1PR2S1PR4S1PR1
SCHEMBL23929261 0.80 TSHR (0.93) ALDH1A1TSHRS1PR2S1PR4S1PR1
SCHEMBL23929276 0.80 TSHR (0.93) ALDH1A1TSHRS1PR2S1PR4S1PR1
SCHEMBL23929263 0.80 TSHR (0.93) ALDH1A1TSHRS1PR2S1PR4S1PR1
SCHEMBL22288098 0.80 TSHR (0.93) ALDH1A1TSHRS1PR2S1PR4S1PR1
SCHEMBL22288104 0.80 TSHR (0.93) ALDH1A1TSHRS1PR2S1PR4S1PR1
SCHEMBL22835051 0.80 TSHR (0.93) ALDH1A1TSHRS1PR2S1PR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4310683-A Sulfosuccinate diesters WITCO CHEMICAL CORPORATION (US) 1982-01-12 US disclosed