Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.48 |
| ▸ | OGFRL1 | Q5TC84 | 6/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596744 | 0.92 | OPRM1 (0.50) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| Acetic Acid SCHEMBL11822954 | 0.87 | OPRM1 (0.49) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| Acetic Acid SCHEMBL11624482 | 0.87 | OPRM1 (0.49) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL11603389 | 0.87 | OPRM1 (0.48) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL11597100 | 0.85 | OPRM1 (0.47) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL11603382 | 0.85 | OPRM1 (0.46) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL11602081 | 0.85 | OPRM1 (0.52) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL11602703 | 0.85 | OPRM1 (0.51) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL11165240 | 0.84 | OPRM1 (0.50) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL11874517 | 0.83 | OPRM1 (0.46) | OPRM1OGFRL1OPRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005365-B1 | PYRANO AND THIOPYRANO (3,4-B) INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-01-06 | — | — | EP | disclosed |