Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HMOX1 | P09601 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251782 | 0.95 | KMT2A (0.48) | KMT2AMEN1POLBHMOX1LMNA | |
| SCHEMBL11245347 | 0.88 | HMOX1 (0.50) | KMT2AMEN1POLBHMOX1 | |
| SCHEMBL11245915 | 0.88 | KMT2A (0.46) | KMT2AMEN1POLBHMOX1CYP19A1 | |
| SCHEMBL11243106 | 0.87 | CYP19A1 (0.49) | POLBHMOX1CYP19A1TDP1 | |
| SCHEMBL11242390 | 0.86 | KMT2A (0.44) | KMT2AMEN1POLBHMOX1LMNA | |
| SCHEMBL11244237 | 0.85 | KMT2A (0.43) | KMT2AMEN1POLBHMOX1LMNA | |
| SCHEMBL11243047 | 0.85 | CYP2A6 (0.50) | HMOX1CYP19A1 | |
| SCHEMBL11244588 | 0.85 | HMOX1 (0.60) | HMOX1CYP19A1 | |
| SCHEMBL11231971 | 0.84 | CYP19A1 (0.47) | POLBHMOX1CYP19A1MAPT | |
| SCHEMBL11247617 | 0.84 | MEN1 (0.48) | KMT2AMEN1HMOX1CYP19A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |