Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.62 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | BID | P55957 | 2/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15344602 | 0.94 | PPARA (0.54) | PPARAPPARGALOX5PTGS2HTT | |
| SCHEMBL2427873 | 0.88 | HTT (0.56) | PPARAPPARGHTTKDM4EMEN1 | |
| SCHEMBL27944038 | 0.86 | KAT8 (0.53) | PPARAPPARGPLK1BIDBCL2L1 | |
| SCHEMBL28103139 | 0.86 | KAT8 (0.53) | PPARAPPARGPLK1BIDBCL2L1 | |
| SCHEMBL27944035 | 0.86 | KAT8 (0.53) | PPARAPPARGPLK1BIDBCL2L1 | |
| SCHEMBL14836221 | 0.86 | KAT8 (0.53) | PPARAPPARGPLK1BIDBCL2L1 | |
| SCHEMBL27944047 | 0.86 | KAT8 (0.53) | PPARAPPARGPLK1BIDBCL2L1 | |
| SCHEMBL8757448 | 0.86 | KAT8 (0.53) | PPARAPPARGPLK1BIDBCL2L1 | |
| SCHEMBL27924694 | 0.86 | KAT8 (0.53) | PPARAPPARGPLK1BIDBCL2L1 | |
| SCHEMBL27924691 | 0.86 | KAT8 (0.53) | PPARAPPARGPLK1BIDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342875-A | STABILIZERS FOR OLEFIN POLYMERS | CINCINNATI-MILACRON, INC. (US) | 1982-08-03 | — | — | US | disclosed |