Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245246 | 0.94 | PPARA (0.62) | PPARAHTTKDM4EKMT2APPARG | |
| SCHEMBL2427873 | 0.90 | HTT (0.56) | PPARAHTTKDM4EKMT2APPARG | |
| SCHEMBL22560183 | 0.88 | LMNA (0.51) | PPARAHTTKDM4EALDH1A1HPGD | |
| SCHEMBL9047654 | 0.86 | HTT (0.47) | PPARAHTTKDM4EKMT2APPARG | |
| SCHEMBL6617354 | 0.86 | PPARA (0.46) | PPARAHTTKDM4EPPARGALDH1A1 | |
| SCHEMBL15344574 | 0.86 | MEN1 (0.49) | PPARAHTTKDM4EKMT2AMEN1 | |
| SCHEMBL3827916 | 0.86 | LMNA (0.52) | PPARAHTTKDM4EKMT2AMEN1 | |
| Acetic Acid SCHEMBL27946451 | 0.85 | PPARA (0.54) | PPARAKDM4EPPARGCA12CA1 | |
| SCHEMBL15344608 | 0.85 | LTB4R (0.52) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL679426 | 0.85 | TSHR (0.49) | PPARAKDM4EKMT2APPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569195-B2 | Internal and external donor compounds for olefin polymerization catalysts II | BASF CORPORATION (US) | 2013-10-29 | — | — | US | claimed |
| EP-2782938-B1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF CORP (US) | 2016-08-31 | — | — | EP | disclosed |