SCHEMBL11245313

SCHEMBL11245313

CNN1C(=O)c2cccc3c(O)ccc(c23)C1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.56
MEN1 O00255 9/20 0.56
USP2 O75604 7/20 0.56
MAPT P10636 6/20 0.56
KEAP1 Q14145 5/20 0.56
NFE2L2 Q16236 5/20 0.56
RECQL P46063 3/20 0.56
LMNA P02545 3/20 0.56
ATM Q13315 3/20 0.56
RGS12 O14924 2/20 0.56
HTT P42858 2/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
BLM P54132 1/20 0.56
ALDH1A1 P00352 6/20 0.51
POLB P06746 4/20 0.51
CYP1B1 Q16678 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
PKM P14618 1/20 0.51
CACNA1B Q00975 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11711964 0.85 KMT2A (0.52) KMT2AMEN1USP2MAPTKEAP1
SCHEMBL11713473 0.84 NPC1 (0.66) KMT2AMEN1USP2MAPTKEAP1
SCHEMBL9006289 0.83 KMT2A (0.65) KMT2AMEN1USP2MAPTKEAP1
SCHEMBL13495358 0.82 KMT2A (0.55) KMT2AMEN1USP2MAPTKEAP1
SCHEMBL11713604 0.81 KMT2A (0.51) KMT2AMEN1USP2MAPTKEAP1
SCHEMBL11256741 0.81 KMT2A (0.64) KMT2AMEN1USP2MAPTKEAP1
SCHEMBL11711675 0.81 KMT2A (0.54) KMT2AMEN1USP2MAPTKEAP1
SCHEMBL11715092 0.81 MEN1 (0.54) KMT2AMEN1USP2MAPTKEAP1
SCHEMBL11717142 0.80 PRMT1 (0.70) KMT2AMEN1USP2MAPTKEAP1
SCHEMBL10701883 0.79 KMT2A (0.59) KMT2AMEN1USP2MAPTKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0023666-B1 ANTHRAQUINONE-AZOMETHINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AS WELL AS A PROCESS FOR PIGMENTING ORGANIC MACROMOLECULAR MATERIALS BAYER AG (DE) 1982-10-13 EP disclosed
US-4323670-A Anthraquinone-azomethine compounds, processes for their preparation and processes for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1982-04-06 US disclosed
EP-0023666-A1 Anthraquinone-azomethine compounds, process for their preparation as well as a process for pigmenting organic macromolecular materials BAYER AG (DE) 1981-02-11 EP disclosed